Web30. mar 2024 · In a real-life clinic setting study aimed at determining phenotypic associations of mucus plugging in moderate to severe asthma patients, those with mucus plugging had worse lung function, more frequent severe exacerbations needing oral corticosteroids, and higher T2 biomarkers. WebRecently, a definition and assessment of a new phenotype comprising patients with overlapping features of asthma and COPD has been suggested and is known as “asthma COPD overlap syndrome”. Several other phenotypes have been proposed, but require validation against clinical outcomes.
Phenotyping asthma: More complex than just age
Web10. apr 2024 · Asthma is a chronic inflammatory disease involving bronchial hyperreactivity and variable, totally or partially reversible obstruction of airflow, which may give rise to episodes of dyspnea, wheezing, and exacerbations or attacks [ 1 ]. WebThis severe uncontrolled asthma carries a tenfold higher risk of mortality. This severe group of asthmatics require oral corticosteroids (OCS) which in turn can lead to its dependence and have serious irreversible adverse effects including weight gain, osteoporosis, diabetics, etc.. Thus, phenotyping of bronchial asthma carries great importance. the consulate email
Understanding Asthma Phenotypes, Endotypes, and Mechanisms of ... - PubMed
WebAsthma is a chronic inflammatory disease of the airways that is challenging to dissect into subgroups because of the heterogeneity present across the spectrum of the disease. … WebDive into the research topics of 'Identification of Asthma Phenotypes in the Spanish MEGA Cohort Study Using Cluster Analysis'. Together they form a unique fingerprint. ... Cluster Analysis 100%. Asthma 86%. Cohort Studies 76%. Phenotype 67%. Lung 23%. Smokers 18%. Nasal Polyps 14%. Treatment Adherence and Compliance 12%. Social Class 10%. Age ... WebThis severe uncontrolled asthma carries a tenfold higher risk of mortality. This severe group of asthmatics require oral corticosteroids (OCS) which in turn can lead to its dependence … the consulate general of the netherlands