Cisplatin pubmed

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WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the … WebThe TPF triplet regimen (docetaxel, cisplatin, and 5‐FU) has a trend of further improving treatment efficacy compared with the traditional doublet regimen. 35 , 36 In a phase II study, concurrent chemoradiotherapy with TPF achieved a clinical CR rate of 52.4%, much higher than the previously reported CR rate of 20%. 9 However, the high ...

Cisplatin and Pemetrexed Have Distinctive Growth-inhibitory ... - PubMed

WebGemcitabine and cisplatin plus durvalumab are being evaluated in the phase 3, TOPAZ … WebCisplatin is a highly effective antitumor drug generally used in the treatment of solid … how many indians lived in north america

A phase II trial of radiation therapy and weekly cisplatin ... - PubMed

WebCisplatin and MD-805 were loaded in the films by casting the polymer solution containing … WebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular … WebAbstract Objectives: To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic response when used for the primary treatment of locally-advanced vulvar carcinoma. howard g buffet foundation glassdoor

Targeted therapy for cisplatin‐resistant lung cancer via …

Oral vinorelbine and cisplatin with concurrent radiotherapy after ...

WebThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon-like peptide-1 receptor agonist (GLP-1R), w … WebCisplatin has dramatically improved the survival rate of cancer patients, but it has also … howard g buffettWebCisplatin and MD-805 were loaded in the films by casting the polymer solution containing the drugs. Fractions of the drugs released from the PLA-CL films were governed by the initial loading, the film thickness, and the polymer molecular weight. The drug release profiles obeyed the classical Fickian diffusion equation at least in the early ... how many indians in uganda

"WebCisplatin is one of the most widely used antineoplastic agents in the treatment of solid tumour and haematological malignancies, including cancers of the testes, ovary, bladder, head and neck, oesophagus, stomach and lung, as well as lymphoma and osteosarcoma. " - Cisplatin pubmed

Cisplatin pubmed

Cellular responses to Cisplatin-induced DNA damage - PubMed

WebMar 2, 2024 · Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer … Web1. INTRODUCTION. Lung cancer has a high worldwide prevalence and is usually malignant, with the highest cancer‐related mortality. 1 , 2 Lung cancers can be grossly classified into non‐small cell lung carcinoma (NSCLC), accounting for about 85% of lung cancers, and small cell lung carcinoma, which is less prevalent. NSCLC can be further divided into …

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WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … WebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and …

WebFerroptosis had great potential to become a new approach in anti-tumor therapies and make up for some classic drugs, which open up a new way for their utility in clinic. Keywords: Cisplatin; Erastin; Ferroptosis; Glutathione; Glutathione … WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an …

WebCisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc.

WebFeb 5, 2024 · Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions. …

WebCisplatin is a widely used anti-cancer drug that is exceptionally effective against … howard g buffett foundation 990WebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … howard g buffett foundation endowmentWebCisplatin (Platinol) has an important dose-response relationship in ovarian cancer. We … howard g. buffettWebAims: This study investigated the regulatory effect of Mitofusin2 (Mfn2) on mitochondria-associated endoplasmic reticulum membrane (MAMs) integrity and cellular injury in cisplatin-induced acute kidney injury (CP-AKI). Results: CP- AKI mice exhibited decreased expression of Mfn2, increased expression of phosphorylated adenosine monophosphate … howard g. buffett foundation grantsWebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class … howard g buffett foundation addressWebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and contraindications for cisplatinum as a valuable agent in treating malignancy. how many indians live in australiaWebCisplatin induces apoptosis of A549 cells by downregulating peroxidase V Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. Cisplatin treatment induces the ROS production, increases the apoptotic rate and downregulates the Prx expression in A549 cells. howard g buffett foundation jobs