WebIntermolecular reactions of N-alkoxycarbonyliminium ions with propargyltrimethylsilane mainly lead to 6-(trimethylsilyl)methyl-3,4-dihydro-2H-1,3-oxazinones, formed by intramolecular trapping of a stabilized β-silyl vinylic cation. α-Allenyl carbamates are obtained as minor products. The oxazinone/allene ratio is dependent on the nature of the … WebDec 15, 2011 · Three-in-one: The nickel-catalyzed asymmetric three-component coupling of 1,3-dienes, aldehydes, and a silylborane in the presence of a chiral phosphoroamidite ligand has been realized. The reaction proceeds by σ-bond metathesis of an oxanickelacycle intermediate with the silylborane to afford the corresponding α-chiral …
Synthesis of α-tertiary allylsilanes by palladium-catalyzed ...
WebGraphical Abstract. Asymmetric catalytic reactions: The first allylsilane reagent-controlled divergent asymmetric Hosomi–Sakurai conjugate allylation and hetero-Diels–Alder … WebAllylsilane 7 (prepared and employed as a 2:1 mixture of diastereomers), derived from pseudoephedrine, has been shown to be a highly effective reagent for the … Larry E. Overman, Daniel J. Ricca, in Comprehensive Organic Synthesis, … did jesus have two natures
Copper-Catalyzed Enantioselective Borylative Allyl–Allyl Coupling …
WebA chiral spiro-bisoxazoline ligand has proven to be an optimal ligand for an asymmetric iron-catalyzed enantioselective Si-H bond insertion reaction of α-diazoesters to provide chiral … WebSep 1, 2005 · Woerpel and coworkers have previously described a kinetic resolution in a double asymmetric [3+2] annulation reaction of a racemic allylsilane and a chiral auxiliary-bearing α-keto ester to prepare highly-substituted tetrahydrofurans as single enantiomers. 21 Our methodology is complementary in that it takes advantage of the stereochemistry ... WebLeighton’s Chiral Allylation Reagents. Daniel Weibel, Ph.D. Merck KGaA, Darmstadt, Germany. The asymmetric allylation of carbonyl compounds remains one of the most … did jesus have water during his 40 day fast